Chromosome scale haplotype assemblies of genomes with HiFi and Omni-C technologies from whatshap Watch Video
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⏲ Duration: 10 min 47 sec ✓ Published: 30-Nov-2020
Description: Haplotype-resolved assembly provides a complete picture of genomes and genetic variations. Most of the existing assembly algorithms either provide haplotype collapsed assembly or require pedigree information for phasing. Approaches such as HapCut2 and WhatsHap require high-quality reference genome to phase variants. Species sequenced from wild-type usually don’t have pedigree information or the high-quality reference genome which prohibits chromosome-wide haplotype phasing. New long-range sequ
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